To get to Nueva Palmira from Montevideo, you can take Route 1 west until you reach the city of Colonia del Sacramento.
From there, take Route 21 north until you reach Nueva Palmira.
It can also be reached from the city of Rosario in Argentina, crossing the Uruguay River by ferry to the city of Carmelo, and then continuing east by car along Route 21 for about 35 km until reaching Nueva Palmira.
See more about how to get to Nueva Palmira
See also information on Carmelo, Colonia del Sacramento, Rosario, Montevideo y Argentina.